november 2018

HF Clinical Case - Mr. John [English]

John Mario

56 years

About this case

Male patient, fully autonomous in daily activities. He is being accompanied in the heart clinic since the beginning of the year due to ischemic heart failure.


Systolic (congestive) heart failure


-20% risk of mortality and -21% risk of hospitalization

Sacubitril/Valsartan prescribed

This action is correct. According to PARADIGM-HF (2016), comparing to enalapril, sacubitril-valsartan was associated to: - 20% reduction of the risk of cardiovascular death; - 21% reduction of the risk of first hospitalization due to heart failure decompensation; - 16% reduction of all cause mortality; - reduction of symptoms and NYHA class.

More information

Case author


Novartis Netherlands