may 2020 • American Journal of Obstetrics and Gynecology

Universal SARS-CoV-2 testing of pregnant women admitted for delivery in two Italian regions.

Gagliardi L, Danieli R, Suriano G, Vaccaro A, et al.

DOI: 10.1016/j.ajog.2020.05.017.

Content curated by::Joana Vaz

Key message

Apesar da prevalência no estudo Londrino ser metade da reportada no de NY (7% vs 15%, talvez por haver menor transmissão na comunidade e maior variedade de étnicas de mulheres que se apresentaram em hospitais em NY) a proporção de assintomáticas foi similar (Londres 88.9% vs NY 87.9%). Já o estudo Italiano sugere prevalência muito menor (0.56%) mas percentagens de assintomáticas similar aos estudos anteriores (cerca de 75%). Mulheres grávidas que se apresentam num hospital para o parto são uma fonte de informação única, uma vez que se apresentam independentemente do factor doença (na maioria dos casos). O screening universal nesta população é encorajado, podendo continuar a ajudar nas estimativas para a população geral, podendo também ajudar no controlo de infecção, gestão do uso de EPI e transmissão nosocomial.

Abstract

Since the early days of the COVID-19 pandemic, substantial undocumented infection has been thought to contribute to the dissemination of SARS-CoV2,[1] with estimated percentages of undocumented infections of 72 to 90%.[1-3] Italy has been the first western country to be massively hit by the pandemic. On March 11th, the Italian government ordered the country lockdown, which is still in place. This led to a flattening and eventually to a reduction of the pandemic curve. Starting by the end of March, several hospitals have begun universal SARS-CoV-2 screening on all admitted patients. Women admitted for delivery represent a peculiar population and a unique source of information, as they come to hospital independently of illness and of their decision. They can therefore provide useful estimates of the circulation of the virus in the general population, despite a possible different social behavior, especially near delivery. The objective of this study was to estimate the “true” SARS-CoV2 infection rate among women admitted for delivery and estimate the burden of undocumented infections in this population.