march 2020 • JAMANETWORK

Profitability of Large Pharmaceutical Companies vs Other Large Public Companies

Ledley FD, McCoy S, Vaughan G, et al.

DOI: 10.1001/jama.2020.0442


This study uses data from annual financial reports to compare the profitability of large pharmaceutical companies vs other large companies in the S&P 500 Index from 2000 to 2018, measured via gross profit; earnings before interest, taxes, depreciation, and amortization; and net income (earnings).